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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF280C All Species: 27.88
Human Site: S423 Identified Species: 87.62
UniProt: Q8ND82 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8ND82 NP_060136.1 737 83096 S423 Q V C Q F R S S T F S D V E A
Chimpanzee Pan troglodytes XP_001171688 979 109275 S428 Q V C N Y R S S S F S D V E T
Rhesus Macaque Macaca mulatta XP_001092864 739 83383 S425 Q V C Q F R S S T F S D V E A
Dog Lupus familis XP_538171 738 83289 S427 Q V C Q F R S S T F S D V E S
Cat Felis silvestris
Mouse Mus musculus Q6P3Y5 742 83128 S430 Q V C Q F R S S I F S D V E T
Rat Rattus norvegicus XP_001069185 737 82705 S424 Q V C Q F R S S I F S D V E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413961 1060 119712 S422 Q V C N Y R S S A F S D V E T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684543 878 97725 S456 Q V C N Y R S S F F C D V D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 94.5 76.6 N.A. 65.7 66.2 N.A. N.A. 38.1 N.A. 32.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.6 96.4 85.7 N.A. 76.5 77.6 N.A. N.A. 47.8 N.A. 47 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 100 93.3 N.A. 86.6 86.6 N.A. N.A. 73.3 N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 86.6 86.6 N.A. N.A. 80 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 25 % A
% Cys: 0 0 100 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 100 0 13 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 88 0 % E
% Phe: 0 0 0 0 63 0 0 0 13 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 38 0 0 0 0 0 0 0 0 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 100 0 0 63 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 100 100 13 0 88 0 0 0 13 % S
% Thr: 0 0 0 0 0 0 0 0 38 0 0 0 0 0 50 % T
% Val: 0 100 0 0 0 0 0 0 0 0 0 0 100 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _